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Introducing OpenAnesthesia Summaries

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on high-yield topics in anesthesiology, critical care,
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Keyword of the Day

SBE prophylaxis indications

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Question of the Day

Systemic levels of mepivacaine would MOST likely be the greatest 10 minutes after which of the following regional techniques using an equal volume of 1.5% mepivacaine?

Question of the Day

Explanation

Systemic absorption of a local anesthetic is determined by the site of injection, the concentration and volume of local anesthetic, the addition of vasoconstricting additives, and the pharmacologic profile of local anesthetic. Generally speaking, the more vascular the region the higher the blood levels after injection. Absorption from the intercostal space is rapid, with plasma concentrations peaking as quickly. Many people use the acronym "ICE-BS" (Intercostal -- Caudal -- Epidural - Brachial plexus - Spinal) to remember fastest to slowest systemic absorption.

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