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Summary of the Day

Cardiac arrest: Induced hypothermia

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Question of the Day

Which of the following MOST likely increases the MAC of sevoflurane?

Question of the Day
Which of the following MOST likely increases the MAC of sevoflurane?
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Explanation

Patients with red hair tend to have a higher MAC than patients with dark hair. In a study of 20 female patients (10 with “bright” red hair and 10 with dark hair), the desflurane concentration required to prevent movement to a standardized noxious electrical stimulation was 6.2 % in redheads compared to 5.2% dark-haired women. Anemia and hypotension, unless sufficiently severe to cause tissue hypoxia, does not change MAC. The duration of anesthesia has no impact on MAC. Tachyphylaxis does not develop and MAC is the same at the beginning of anesthetic as it is at the end.

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