Peripheral nerves have three layers of connective tissue:
- Epineurium – is the outermost layer of connective tissue that is continuous with the dura mater. It also includes the connective tissue in between any fascicles (bundles) within the nerve.
- Perineurium – is the connective tissue sheath that surrounds a fascicle of axons.
- Endoneurium – is the delicate connective tissue fibers that surround individual axons.
Defined by: Ravi Balireddy, MD