Search on website
chevron-left-black Keywords

SSEP Latency: anesthetic drugs

Inhalational anesthetics (halogenated anesthetics and nitrous oxide) decrease the amplitudes and increase the latency of SSEPs in a dose-dependent manner. (1)

Midazolam has little effect below 150mcg/kg.

Propofol has minimal effects between 120-200mcg/kg/min

Ketamine and Etomidate are acceptable as well.(2)

Opioids have minimal effects on SSEPs or MEPs.

At higher doses: (3)

  • Etomidate increasesboth amplitude and latency.
  • Thiopental decreasesamplitude and increases
  • Midazolam hasno effect on amplitude but increases

Dexmedetomidine has minimal effects on SSEP monitoring. (4)

Other References

  1. Recommendations of the International Society of Intraoperative Neurophysiology for intraoperative somatosensory evoked potentials. Link