Paired vs. unpaired t-test
Last updated: 03/09/2015
Paired t-test compares study subjects at 2 different times (paired observations of the same subject). Unpaired t-test (aka Student’s test) compares two different subjects. The paired t-test reduces intersubject variability (because it makes comparisons between the same subject), and thus is theoretically more powerful than the unpaired t-test.
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