Preeclampsia: Lab abnormalities

• Proteinuria of:

  • >300 mg/24 h (mild preeclampsia)
  • >5 g/24 h (severe preeclampsia)
  • Urine dipstick >1+ 

• Protein/creatinine ratio >0.3
• Serum uric acid >5.6 mg/dL
• Serum creatinine >1.2 mg/dL
• Low platelets/coagulopathy
• Platelet count <100,000/mm3
• Elevated PT or aPTT
• Decreased fibrinogen
• Increased d-dimer

HELLP syndrome – a variant of severe preeclampsia and defined by the following:

• Hemolysis
• Abnormal peripheral smear
• Indirect bilirubin >1.2 mg/dL
• Lactate dehydrogenase >600 U/L
• Elevated Liver enzymes Serum AST >70 U/L
• Low Platelets count <100,000/mm