ARDS: Techniques of ventilation

Ventilatory strategies in patients with ARDS (Acute Respiratory Distress Syndrome) are based on clinical trial data from numerous large prospective clinical trials. Current strategies focus on:

  • Limiting tidal volume (6ml/kg predicted body weight) to avoid volutrauma
    • Formula for predicted body weight: Males: PBW (kg) = 50 + 2.3 (height (in) – 60); Females: PBW (kg) = 45.5 + 2.3 (height (in) – 60) (See:
  • Higher positive end-expiratory pressure (PEEP) (typically 6-12cmH2O) to augment oxygenation & avoid ‘atelectrauma’
  • Limiting end-inspiratory (plateau) pressures to avoid alveolar barotrauma- plateau pressures should be limited to 30cmH2O

Similiar Keywords

  • ARDS: Ventilation management
  • Lung protect vent: Pressure goal


  1. Sutherasan Y, Vargas M, Pelosi P. Protective mechanical ventilation in the non-injured lung: review and meta-analysis. Critical Care 2014, 18:211  doi:10.1186/cc13778
  2. Amato MB, Meade MO, Slutsky AS, Brochard L, Costa EL, Schoenfeld DA, Stewart TE, Briel M, Talmor D, Mercat A, Richard JC, Carvalho CR, Brower RG. Driving pressure and survival in the acute respiratory distress syndrome. N Engl J Med. 2015 Feb 19; 372(8): 747-55.