Definition
The initial metabolite of succinylcholine (SCh), succinylmonocholine, produces a tranisent negative chronotropic effect through its stimulation of sinus node muscarinic receptors. Repeated dosing or infusions of SCh may lead to bradycardia that is appropriately treated with atropine.
Subspecialty
Related Media
Keyword history
91%/2009
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Sources
PubMed
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I Yasuda, T Hirano, K Amaha, H Fudeta, S Obara Chronotropic effects of succinylcholine and succinylmonocholine on the sinoatrial node. Anesthesiology: 1982, 57(4);289-92