Fetal supply of blood is facilitated by three factors:
Oxygen concentration and partial pressure gradient within the feto-maternal circulatory system
Fetal hemoglobin (HbF), which has higher affinity (lower P50 of 19mmHg) for oxygen then adult hemoglobin (HbA) with a P50 of 26.8mmHg. This facilitates transfer oxygen transfer from mother to fetus.
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