Acetylcholine receptor anatomy

The acetylcholine receptor (AChR) is a membrane protein that binds to the neurotransmitter acetylcholine (Ach). These receptors can be divided into two main types of distinct receptors, nicotinic and muscarinic. Nicotinic acetylcholine receptors (nAChR) are pentameric ligand-gated ion channels, whereas muscarinic acetylcholine receptors (mAChR) are seven-helix G-protein coupled membrane proteins. [More…]